A zwitterionic squaraine dye with a large Stokes shift for in vivo and site-selective protein sensing

• DOI: 10.1039/c2cc36285f
• Publication Date: 2012-10-08T08:31:23Z
• Authors: Yongqian Xu; Qin Liu; Xiaopeng Li; Chrys Wesdemiotis; Yi Pang
• Keywords: Stokes shift; Substructure

A novel squaraine dye (SQ) exhibits improved fluorescence response toward protein detection by incorporation of a zwitterionic structure. With the aid dansylamide (DNSA) substituent, new probe (DNSA-SQ) remarkable selectivity in binding to site I (a specific substructure protein).