A disulfide-linked conjugate of ferrocenyl chalcone and silicon(iv) phthalocyanine as an activatable photosensitiser

• DOI: 10.1039/c2cc37251g
• Publication Date: 2012-11-07T16:00:29Z
• Authors: Janet T. F. Lau; Xiong-Jie Jiang; Dennis K. P. Ng; Pui-Chi Lo
• Keywords: Chalcone; Dithiothreitol; Conjugate; Linker; Phthalonitrile

A novel bis(ferrocenyl chalcone) silicon(IV) phthalocyanine has been prepared in which the disulfide linker can be cleaved by dithiothreitol. The separation of ferrocenyl quencher and core greatly enhances fluorescence emission, singlet oxygen production vitro photocytotoxicity.