CuBr for KA2 reaction: en route to propargylic amines bearing a quaternary carbon center
Bromides
Propylamines
Ketones
01 natural sciences
Carbon
Catalysis
0104 chemical sciences
Pargyline
Alkynes
Amines
Copper
DOI:
10.1039/c3cc45301d
Publication Date:
2013-08-01T12:33:14Z
AUTHORS (3)
ABSTRACT
A highly efficient CuBr-catalyzed coupling of ketones, amines and alkynes (KA(2)) forming propargylic amines bearing a quaternary carbon center with the broadest scope so far has been developed.
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