Unprecedented ortho-acylation of azoxybenzenes with α-oxocarboxylic acids by Pd-catalyzed C–H activation and decarboxylation

• DOI: 10.1039/c3cc45492d
• Publication Date: 2013-08-08T10:04:52Z
• Authors: Hongji Li; Pinhua Li; Qiong Zhao; Lei Wang
• Keywords: Acylation; Stereoisomerism; Azo Compounds; Decarboxylation; 01 natural sciences; Carbon; Catalysis; Palladium; Hydrogen; 0104 chemical sciences

A palladium-catalyzed ortho-acylation reaction of azoxybenzenes with α-oxocarboxylic acids was developed in the presence of K2S2O8. The established methodology provides a direct approach to obtain acylated azoxybenzenes in good yields.