Folic acid conjugated self-assembled layered double hydroxide nanoparticles for high-efficacy-targeted drug delivery

• DOI: 10.1039/c3cc45714a
• Publication Date: 2013-10-02T16:43:23Z
• Authors: Li Yan; Wei Chen; Xiaoyue Zhu; Longbiao Huang; Zhigang Wang; Guangyu Zhu; V. A. L. Roy; K. N. Yu; Xianfeng Chen
• Keywords: Layered double hydroxides

Enhanced selectivity and efficacy is important for advanced drug delivery. Herein, a novel type of folic acid conjugated self-assembled layered double hydroxide nanoparticles reported. These have loading capacity 27 wt% are able to enter cell nuclei dramatically improve the MTX.