One step synthesis of benzoxazepine derivatives via a PPh3 catalyzed aza-MBH domino reaction between salicyl N-tosylimines and allenoates

• DOI: 10.1039/c3cc46379f
• Publication Date: 2013-09-23T13:42:55Z
• Authors: Hongxia Zhao; Xiangtai Meng; You Huang
• Keywords: Domino; Cascade reaction; Reaction conditions

PPh3-Catalyzed aza-MBH domino reaction of salicyl N-tosylimines with γ-CH3 substituted allenoates is reported. Readily available imines and are converted to benzoxazepine derivatives in one step. Wherein, functionalization C–H bonds γ-substituted allenoate has been developed this process.