Temperature-controlled release by changes in the secondary structure of peptides anchored onto mesoporous silica supports

• DOI: 10.1039/c3cc49421g
• Publication Date: 2014-01-31T13:32:35Z
• Authors: Cristina de la Torre; Alessandro Agostini; Laura Mondragón; Mar Orzáez; Félix Sancenón; Ramón Martínez-Máñez; María D. Marcos; Pedro Amorós; Enríque Pérez-Payá
• Keywords: Models, Molecular; Responsive Controlled-Release; INGENIERIA DE LA CONSTRUCCION; Surface Properties; QUIMICA INORGANICA; Temperature; 02 engineering and technology; Silicon Dioxide; Valves; Protein Structure, Secondary; Chemistry; QUIMICA ORGANICA; Nanoparticles; Combinatorial library; Particle Size; Amino-acids; Peptides; 0210 nano-technology; Porosity

Changes in the conformation of a peptide anchored onto external surface MCM-41 nanoparticles are used to design temperature-controlled delivery systems.