A fluorescent light-up probe with AIE characteristics for specific mitochondrial imaging to identify differentiating brown adipose cells

• DOI: 10.1039/c4cc00452c
• Publication Date: 2014-06-09T14:08:48Z
• Authors: Meng Gao; Choon Kiat Sim; Chris Wai Tung Leung; Qinglian Hu; Guangxue Feng; Feng Xu; Ben Zhong Tang; Bin Liu
• Keywords: 2. Zero hunger; Hydrazines; Adipose Tissue, Brown; Microscopy, Fluorescence; Cell Survival; Humans; Cell Differentiation; Pyridinium Compounds; 01 natural sciences; Fluorescent Dyes; Mitochondria; 0104 chemical sciences

We report the design and synthesis of a specific mitochondrial fluorescent probe AIE-MitoGreen-1 with AIE characteristics to monitor the mitochondrial morphology changes and identify the differentiation process of living brown adipose cells.