Highly effective copper-mediated gem-difluoromethylenation of arylboronic acids
Hydrocarbons, Fluorinated
Boronic Acids
Methylation
01 natural sciences
Copper
0104 chemical sciences
3. Good health
DOI:
10.1039/c4cc03321c
Publication Date:
2014-06-03T09:44:32Z
AUTHORS (7)
ABSTRACT
A simple and highly efficient Cu-mediated gem-difluoromethylenation of a variety of aryl boronic acids with bromodifluoromethylated heterocyclic compounds has been disclosed. The transformations were performed in air at room temperature without ligands, bases, or additives.
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