4-Halogeno-sydnones for fast strain promoted cycloaddition with bicyclo-[6.1.0]-nonyne

• DOI: 10.1039/c4cc03816a
• Publication Date: 2014-06-30T15:31:21Z
• Authors: Lucie Plougastel; Oleksandr Koniev; Simon Specklin; Elodie Decuypere; Christophe Créminon; David-Alexandre B...; Alain Wagner; Sergii Kolodych; Frédéric Taran
• Keywords: Bioorthogonal Chemistry; Strain (injury)

4-Halogeno-sydnones were found to be efficient dipole partners for the strain promoted click reaction with bicyclo-[6.1.0]-nonyne. This bioorthogonal has been applied protein labeling.