Visual electrochemiluminescence detection of telomerase activity based on multifunctional Au nanoparticles modified with G-quadruplex deoxyribozyme and luminol

• DOI: 10.1039/c4cc06302c
• Publication Date: 2014-08-29T13:01:03Z
• Authors: Huai-Rong Zhang; Yin-Zhu Wang; Mei-Sheng Wu; Qiu-Mei Feng; Hai-Wei Shi; Hong-Yuan Chen; Jing-Juan Xu
• Keywords: Electrochemiluminescence; Deoxyribozyme; Luminol; G-quadruplex

A novel visual electrochemiluminescence (ECL) analysis strategy for detection of telomerase activity is reported on a microarray chip, with G-quadruplex deoxyribozyme (DNAzyme) and luminol modified Au nanoparticles (NPs) as double-catalytic amplification labels.