Translation of off-target effects: prediction of ADRs by integrated experimental and computational approach

• DOI: 10.1039/c4tx00077c
• Publication Date: 2014-08-11T09:02:03Z
• Authors: Laszlo Urban; Mateusz Maciejewski; Eugen Lounkine; Steven Whitebread; Jeremy L. Jenkins; Jacques Hamon; Alexander Fekete; Patrick Y. Muller
• Keywords: Drug reaction; Drug Development

Adverse drug reactions (ADRs) are associated with most drugs, often discovered late in development and sometimes only during extended course of clinical use.