Curcumin loaded mesoporous silica: an effective drug delivery system for cancer treatment

• DOI: 10.1039/c5bm00552c
• Publication Date: 2015-12-16T16:01:58Z
• Authors: Rajesh Kotcherlakota; Ayan Kumar Barui; Sanjiv Prashar; Mariano Fajardo; David Briones; Antonio Rodríguez...; Chitta Ranjan Patra; Santiago Gómez-Ruiz
• Keywords: Curcumin; Cell Survival; Antineoplastic Agents; Apoptosis; Silicon Dioxide; 01 natural sciences; 0104 chemical sciences; 3. Good health; Drug Delivery Systems; Humans; Nanoparticles; Poly(ADP-ribose) Polymerases; Porosity

Mesoporous silica material based drug delivery systems (DDSs) containing curcumin show biocompatibility in normal cells and an effective anti-cancer effect in cancer cells.