Antibacterial properties and atomic resolution X-ray complex crystal structure of a ruthenocene conjugated β-lactam antibiotic

• DOI: 10.1039/c5cc00904a
• Publication Date: 2015-03-02T14:01:23Z
• Authors: Eric M. Lewandowski; Joanna Skiba; Nicholas J. Torelli; Aleksandra Rajnisz; Jolanta Solecka; Konrad Kowalski; Yu Chen
• Keywords: Ruthenocene; Lactam

Crystal structure of β-lactam product complex with CTX-M-14 E166A mutant sheds light on β-lactamase catalysis and ruthenocene binding by proteins.