Mitochondria-targeted fluorescent thermometer monitors intracellular temperature gradient

• DOI: 10.1039/c5cc01088h
• Publication Date: 2015-04-03T17:59:19Z
• Authors: Satoshi Arai; Madoka Suzuki; Sung-Jin Park; Jung Sun Yoo; Lu Wang; Nam-Young Kang; Hyung-Ho Ha; Young-Tae Chang
• Keywords: 570; 0303 health sciences; Molecular Structure; RHODAMINE-B; ENDOPLASMIC-RETICULUM; Temperature; THERMOGENESIS; PROTEIN; LIFETIME; 3T3 Cells; Thermometry; Fluorescence; Cell Line; Mitochondria; Mice; 03 medical and health sciences; NANOSCALE; Xanthenes; Animals; Humans; LIVING CELLS; PROBE; Fluorescent Dyes; HeLa Cells

A small molecule fluorescent thermometer targeting mitochondria (Mito thermo yellow) enables us to monitor the intracellular temperature gradient, generated by exogenous heating in various cells.