Direct gem-difluoromethylenation of sp3-hybridized carbon center through copper-mediated radical/radical cross-coupling for the construction of a CH2–CF2 linkage
Bromides
Benzoxazoles
Alkylation
Free Radicals
Hydrocarbons, Fluorinated
01 natural sciences
Catalysis
3. Good health
0104 chemical sciences
Cyclic N-Oxides
Benzyl Compounds
Benzimidazoles
Benzothiazoles
Oxidation-Reduction
Copper
DOI:
10.1039/c5cc05677b
Publication Date:
2015-08-27T10:30:40Z
AUTHORS (9)
ABSTRACT
An efficient gem-difluoromethylenation of benzyl bromides through copper-mediated direct radical/radical C–C cross-coupling has been developed for the construction of CH2–CF2 linkage.
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CITATIONS (13)
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