Asymmetric synthesis of cyclopentanes bearing four contiguous stereocenters via an NHC-catalyzed Michael/Michael/esterification domino reaction

• DOI: 10.1039/c5cc09581f
• Publication Date: 2016-01-05T16:33:25Z
• Authors: Tao Shu; Qijian Ni; Xiaoxiao Song; Kun Zhao; Tianyu Wu; Rakesh Puttreddy; Kari Rissanen; Dieter Enders
• Keywords: Cyclopentanes; Stereocenter; Michael reaction; Domino; Cascade reaction

An NHC-catalyzed Michael/Michael/esterification domino reaction <italic>via</italic> homoenolate/enolate intermediates for the asymmetric synthesis of tetrasubstituted cyclopentanes is described.