UV-nanoimprint lithography as a tool to develop flexible microfluidic devices for electrochemical detection

• DOI: 10.1039/c5lc00515a
• Publication Date: 2015-06-22T10:00:17Z
• Authors: Juhong Chen; Yiliang Zhou; Danhui Wang; Fei He; Vincent M. Rotello; Kenneth R. Carter; James J. Watkins; Sam R. Nugen
• Keywords: Nanoimprint lithography

Research in microfluidic biosensors has led to dramatic improvements sensitivities. Very few examples of these devices have been commercially successful, keeping this methodology out the hands potential users. In study, we developed a method fabricate flexible device containing electrowetting valves and electrochemical transduction. The was designed be amenable roll-to-roll manufacturing system, allowing low cost. Microchannels with high fidelity were structured on PET film using UV-NanoImprint Lithography (UV-NIL). electrodes inkjet-printed photonically sintered second film. bonded directly channel-containing layer form sealed fluidic device. Actuation multivalve system food dye PBS buffer performed demonstrate automated fluid delivery. then used detect Salmonella liquid sample.