Micro-optical coherence tomography tracking of magnetic gene transfection via Au–Fe3O4dumbbell nanoparticles

• DOI: 10.1039/c5nr05459a
• Publication Date: 2015-09-23T08:35:35Z
• Authors: Wei Shi; Xinyu Liu; Chao Wei; Zhichuan J. Xu; Stanley Siong Wei...; Linbo Liu; Chenjie Xu
• Keywords: Dumbbell; HEK 293 cells

Heterogeneous Au–Fe3O4 dumbbell nanoparticles (NPs) are composed of Au NPs and Fe3O4 that bring in optical magnetic properties respectively. This article reports the engineering as gene carriers for transfection well contrast agents micro-optical coherence tomography (μOCT). As a proof-of-concept, used to deliver green fluorescent protein HEK 293T cells their entrance into is monitored through μOCT.