Strong Brønsted acid promoted asymmetric hydrogenation of isoquinolines and quinolines catalyzed by a Rh–thiourea chiral phosphine complex via anion binding

• DOI: 10.1039/c5sc04712a
• Publication Date: 2016-01-26T14:36:27Z
• Authors: Jialin Wen; Renchang Tan; Shaodong Liu; Qingyang Zhao; Xumu Zhang
• Keywords: Asymmetric hydrogenation; Brønsted–Lowry acid–base theory

Catalyzed by a Rh/bisphosphine–thiourea (<bold>L1</bold>) complex, isoquinolines and quinolines are hydrogenated with high conversions enantioselectivities.