Preparation of optimized lipid-coated calcium phosphate nanoparticles for enhanced in vitro gene delivery to breast cancer cells

• DOI: 10.1039/c5tb00912j
• Publication Date: 2015-07-29T11:03:39Z
• Authors: Jie Tang; Li Li; Christopher B. Ho...; Stephen M. Mahler; Leaf Huang; Zhi Ping Xu
• Keywords: 0301 basic medicine; 2500 Materials Science; 2204 Biomedical Engineering; 500; 02 engineering and technology; 1600 Chemistry; 3. Good health; 03 medical and health sciences; Breast cancer; In vitro; Optimized lipid-coated calcium phosphate nanoparticles; 0210 nano-technology

The optimized lipid coated calcium phosphate nanoparticles more efficiently deliver functional siRNA and inhibit the cancer cell growth, in comparison with the commercial transfection agent OligofactamineTM.