Peptide based hydrogels for cancer drug release: modulation of stiffness, drug release and proteolytic stability of hydrogels by incorporating d-amino acid residue(s)

• DOI: 10.1039/c6cc01744d
• Publication Date: 2016-03-08T11:02:06Z
• Authors: Kingshuk Basu; Abhishek Baral; Shibaji Basak; Ashkan Dehsorkhi; Jayanta Nanda; Debmalya Bhunia; Surajit Ghosh; Valeria Castelletto; Ian W. Hamley; Arindam Banerjee
• Keywords: Drug Carriers; Molecular Structure; Cell Survival; Antineoplastic Agents; Hydrogels; 02 engineering and technology; 3. Good health; Drug Liberation; Drug Delivery Systems; Neoplasms; Proteolysis; MCF-7 Cells; Humans; Amino Acids; Peptides; 0210 nano-technology

This is a novel example of tailor-made design of hydrogels for anticancer drug release.