Selective plane illumination microscopy on a chip

• DOI: 10.1039/c6lc00084c
• Publication Date: 2016-03-17T10:32:52Z
• Authors: Petra Paiè; Francesca Bragheri; Andrea Bassi; Roberto Osellame
• Keywords: 0301 basic medicine; femtopsecond laser micromachining; Recombinant Fusion Proteins; microfluidics; Equipment Design; fluorescence microscopy; lab-on-chip; High-Throughput Screening Assays; Histones; Bioengineering; Chemistry (all); Biochemistry; Biomedical Engineering; Luminescent Proteins; 03 medical and health sciences; Imaging, Three-Dimensional; Microscopy, Fluorescence; Lab-On-A-Chip Devices; Spheroids, Cellular; Animals; Humans; Nanoparticles; Single-Cell Analysis; Red Fluorescent Protein

A high-throughput on-chip light sheet microscope allowing 3D reconstructions of large populations samples, even with standard microscopes, is presented.