The dual role of thiourea in the thiotrifluoromethylation of alkenes

• DOI: 10.1039/c6sc02790c
• Publication Date: 2016-09-30T11:00:58Z
• Authors: Paolo Ricci; Tanatorn Khotaviv...; Lukas Pfeifer; Maurice Médebielle; John Richard Morphy; Véronique Gouverneur
• Keywords: Chemistry; 01 natural sciences; 0104 chemical sciences

We report the stereoselective and metal-free trifluoromethylation of alkenes followed by S-cyclization using thiourea as the S-source and SET initiator.