Glioma cell invasion is significantly enhanced in composite hydrogel matrices composed of chondroitin 4- and 4,6-sulfated glycosaminoglycans

• DOI: 10.1039/c6tb01083k
• Publication Date: 2016-08-26T09:13:35Z
• Authors: Meghan T. Logun; Nicole S. Bisel; Emily A. Tanasse; Wujun Zhao; Bhagya Gunasekera; Leidong Mao; Lohitash Karumbaiah
• Keywords: 0301 basic medicine; 03 medical and health sciences

Glioblastoma multiforme (GBM) is the most aggressive form of astrocytoma accounting for a majority of primary malignant brain tumors in the United States.