Single-molecule imaging of telomerase activity via linear plasmon rulers

• DOI: 10.1039/c7cc00626h
• Publication Date: 2017-03-31T10:25:22Z
• Authors: Guang-Sheng Qian; Ting-Ting Zhang; Wei Zhao; Jing-Juan Xu; Hong-Yuan Chen
• Keywords: Linear molecular geometry

Plasmon rulers (PRs) exploit the potential of plasmon coupling between individual pairs noble metal nanoparticles in biological processes, especially single-molecule detection. Herein, for first time, we report a strategy based on Ag PRs situ monitoring extension process telomerase primer (TSP) activated by single telomerase.