Controllable access to multi-substituted imidazoles via palladium(ii)-catalyzed C–C coupling and C–N condensation cascade reactions

• DOI: 10.1039/c7cc05315k
• Publication Date: 2017-08-08T15:33:57Z
• Authors: Haihua Yu; Li Xiao; Xicheng Yang; Liming Shao
• Keywords: 01 natural sciences; 0104 chemical sciences

A novel and efficient protocol for the controllable synthesis of various di-, tri- tetra-substituted imidazoles <italic>via</italic> cascade palladium catalyzed C–C coupling followed by intramolecular C–N bond formation was developed.