Single-step synthesis of styryl phosphonic acids via palladium-catalyzed Heck coupling of vinyl phosphonic acid with aryl halides

• DOI: 10.1039/c7cc05909d
• Publication Date: 2017-10-27T13:34:03Z
• Authors: Brett W. McNichols; Joshua T. Koubek; Alan Sellinger
• Keywords: Heck Reaction

We have developed a single step palladium-catalyzed Heck coupling of aryl halides with vinyl phosphonic acid to produce functionalized (<italic>E</italic>)-styryl acids.