Use of azidonaphthalimide carboxylic acids as fluorescent templates with a built-in photoreactive group and a flexible linker simplifies protein labeling studies: applications in selective tagging of HCAII and penicillin binding proteins

• DOI: 10.1039/c7cc08209f
• Publication Date: 2017-11-06T09:32:58Z
• Authors: Monisha Singha; Sayantani Roy; Satya Deo Pandey; Subhendu Sekhar Bag; Prabuddha Bhattac...; Mainak Das; Anindya S. Ghosh; Debashis Ray; Amit Basak
• Keywords: 0301 basic medicine; Azides; Naphthalimides; 03 medical and health sciences; Molecular Structure; Staining and Labeling; Carboxylic Acids; Humans; Penicillin-Binding Proteins; Photochemical Processes; Carbonic Anhydrases; Fluorescent Dyes

A simple design of versatile template-based protein labeling agents has been successfully demonstrated with HCA and PBPs.