Sustained consumption of cocoa-based dark chocolate enhances seizure-like events in the mouse hippocampus

• DOI: 10.1039/c7fo01668a
• Publication Date: 2018-01-19T03:33:49Z
• Authors: Ana Cicvaric; Tanja Bulat; Daniel Bormann; Jiaye Yang; Bastian Auer; Ivan Milenkovic; Maureen Cabatic; Radoslav Milicevic; Francisco J. Monje
• Keywords: Neurons; 2. Zero hunger; Cacao; Receptors, GABA-A; Hippocampus; 12. Responsible consumption; 3. Good health; Mice, Inbred C57BL; Mice; 03 medical and health sciences; 0302 clinical medicine; Seizures; Animals; Humans; Chocolate

This study characterizes the effects of sustained dark-chocolate consumption on mouse behavior and reveals its potential to induce seizure-like events in the hippocampus, a brain structure critical for memory storage.