Gold–silver alloy semi-nanoshell arrays for label-free plasmonic biosensors

• DOI: 10.1039/c7nr01982c
• Publication Date: 2017-06-14T12:24:32Z
• Authors: Valentina Russo; Niccolo’ Michieli; Tiziana Cesca; Carlo Scian; Davide Silvestri; Margherita Morpurgo; Giovanni Mattei
• Keywords: Nanoshell; Nanosphere lithography; Bimetallic strip; Streptavidin; Biomolecule

Nanosphere lithography coupled with reactive ion etching has been used to synthesize hexagonal ordered arrays of Au-Ag bimetallic semi-nanoshells be as plasmonic biosensors. The degree lateral interaction between adjacent can controlled by tailoring the time in order boost global properties through formation near-field hot-spots, which turn improve sensitivity To test efficiency proposed system a biosensor, we an established protocol for detection biomolecules (local sensitivity), based on receptor-ligand approach and using biotin-streptavidin model system. We also tested homogeneous change refractive index buffer over sensor (bulk sensitivity). Comparing obtained results those array nanoprisms, chosen benchmark, significantly higher performances both local bulk sensitivities have found, agreement electrodynamics simulations finite-element methods.