DNA-binding, molecular docking studies and biological activity studies of ruthenium(ii) polypyridyl complexes

• DOI: 10.1039/c7ra05103d
• Publication Date: 2017-07-13T05:28:40Z
• Authors: Bing Tang; Fang Shen; Dan Wan; Bo-Hong Guo; Yang-Jie Wang; Qiao-Yan Yi; Yun-Jun Liu
• Keywords: Docking (animal)

Three new Ru(<sc>ii</sc>) complexes [Ru(N–N)₂(PTCP)]²⁺ were synthesized and characterized. The DNA-binding, <italic>in vitro</italic> cytotoxicity, apoptosis, autophagy western blot analysis investigated.