Exosomes from LPS-stimulated macrophages induce neuroprotection and functional improvement after ischemic stroke by modulating microglial polarization

• DOI: 10.1039/c8bm01449c
• Publication Date: 2019-03-02T01:04:49Z
• Authors: Yan Zheng; Ruyi He; Peng Wang; Yijie Shi; Liang Zhao; Jia Liang
• Keywords: Lipopolysaccharides; Neurons; 0301 basic medicine; Macrophages; Exosomes; Neuroprotection; Brain Ischemia; 3. Good health; Stroke; Mice; 03 medical and health sciences; Phenotype; RAW 264.7 Cells; Blood-Brain Barrier; Animals; Microglia

Inflammation occurs throughout the progression of cerebral ischemia/reperfusion and mediates myriads of pathological events following an ischemic insult.