Encapsulation of ionic nanoparticles produces reactive oxygen species (ROS)-responsive microgel useful for molecular detection

• DOI: 10.1039/c8cc01432a
• Publication Date: 2018-03-28T16:05:03Z
• Authors: Yang Liu; Yu-Min Wang; Sabrina Sedano; Qiaoshi Jiang; Yaokai Duan; Wen Shen; Jian-Hui Jiang; Wenwan Zhong
• Keywords: Microparticle

Encapsulation of ionic nanoparticles in a hydrogel microparticle, i.e. microgel, produces target-stimulated probe for molecular detection. Selective reactive oxygen species (ROS) release the enclosed cations from microgel which subsequently turn on fluorogenic dyes to emit intense fluorescence, permitting rapid detection ROS or ROS-producing molecules. The ROS-responsive provides advantages simple fabrication, bright and stable signals, easy handling, response, carrying great promise biomedical applications.