Native mass spectrometry goes more native: investigation of membrane protein complexes directly from SMALPs

• DOI: 10.1039/c8cc06284f
• Publication Date: 2018-11-19T14:54:24Z
• Authors: Nils Hellwig; Oliver Peetz; Zainab Ahdash; Igor Tascón; Paula J. Booth; Vedrana Mikusevic; Marina Diskowski; Argyris Politis; Yvonne Hellmich; Inga Hänelt; Eamonn Reading; Nina Morgner
• Keywords: Nanodisc; Maleic acid

Other than more widely used methods, the use of styrene maleic acid copolymers allows direct extraction membrane proteins from lipid bilayer into SMALPs keeping it in its native surrounding.