Palladium(0)-catalyzed C(sp3)–Si bond formation via formal carbene insertion into a Si–H bond

• DOI: 10.1039/c8cc06768f
• Publication Date: 2018-09-18T00:34:12Z
• Authors: Zhenxing Liu; Jingfeng Huo; Tianren Fu; Haocheng Tan; Fei Ye; Mohammad Lokman H...; Jianbo Wang
• Keywords: Insertion reaction; Migratory insertion; Reductive elimination

Pd(0)-Catalyzed formal carbene insertion into Si-H bonds has been achieved as an efficient method for C(sp3)-Si bond formation. The reaction, which uses readily available N-tosylhydrazones the diazo precursors, is highly and shows a wide substrate scope. Rh(ii) Cu(i) salts, are widely used catalysts reactions, have proved to be ineffective current reaction. A Pd(ii) migratory insertion/reductive elimination mechanism proposed.