Fe3O4–ZIF-8 assemblies as pH and glutathione responsive T2–T1 switching magnetic resonance imaging contrast agent for sensitive tumor imaging in vivo

• DOI: 10.1039/c8cc08943d
• Publication Date: 2018-11-29T11:34:44Z
• Authors: Jiaomin Lin; Pengyan Xin; Lu An; Yanjun Xu; Cheng Tao; Qiwei Tian; Zhiguo Zhou; Bing Hu; Shiping Yang
• Keywords: Surface Properties; Liver Neoplasms; Imidazoles; Contrast Media; Hydrogen-Ion Concentration; Glutathione; Magnetic Resonance Imaging; 01 natural sciences; Ferrosoferric Oxide; 0104 chemical sciences; Mice; Zeolites; Animals; Humans; Nanoparticles; Particle Size

Fe₃O₄ nanoparticles were assembled into a zeolitic-imidazole framework to form pH- and glutathione-responsive <italic>T</italic>₂–<italic>T</italic>₁ switching contrast agent for sensitive tumor imaging.