PROTAC-mediated crosstalk between E3 ligases

• DOI: 10.1039/c8cc09541h
• Publication Date: 2019-01-16T12:05:10Z
• Authors: Christian Steinebach; Hannes Kehm; Stefanie Lindner; Lan Phuong Vu; Simon Köpff; Álvaro López Mármol; Corinna Weiler; Karl G. Wagner; Michaela Reichenz...; Jan Krönke; Michael Gütschow
• Keywords: Crosstalk; Ubiquitin-Protein Ligases

Small-molecule heterobifunctional degraders can effectively control protein levels and are useful research tools.