The impact of lipid oxidation on the functioning of a lung surfactant model

• DOI: 10.1039/c8cp04496a
• Publication Date: 2018-09-12T08:04:34Z
• Authors: A. Stachowicz-Kuś...; L. Cwiklik; J. Korchowiec; E. Rogalska; B. Korchowiec
• Keywords: 0301 basic medicine; 2. Zero hunger; 0303 health sciences; pulmonary surfactant; mixed monolayers; low-level ozone; Pulmonary Surfactants; Molecular Dynamics Simulation; Lipid Metabolism; protein interactions; Models, Biological; 3. Good health; molecular-dynamics simulations; 03 medical and health sciences; air-water-interface; oxidized phospholipids; sp-c; phase-behavior; Lung; Oxidation-Reduction; langmuir monolayer

The effects of oxidizing 20 mole% of unsaturated lipids in a lung surfactant model were examined with a combined experimental–theoretical approach.