Computational redesign of penicillin acylase for cephradine synthesis with high kinetic selectivity
Cephradine
Lactam
DOI:
10.1039/c8gc03420f
Publication Date:
2018-11-15T13:51:43Z
AUTHORS (4)
ABSTRACT
A penicillin acylase variant was designed to catalyze the enzymatic synthesis of β-lactam antibiotic cephradine under industrial conditions.
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