Overexpression of the mitochondrial Mg channel MRS2 increases total cellular Mg concentration and influences sensitivity to apoptosis

• DOI: 10.1039/c8mt00050f
• Publication Date: 2018-06-21T09:34:57Z
• Authors: Lucia Merolle; Gerhard Sponder; Azzurra Sargenti; Lucia Mastrototaro; Concettina Cappadone; Giovanna Farruggia; Alessandra Procopio; Emil Malucelli; Pietro Parisse; Alessandra Gianon...; Jörg R. Aschenbach; Martin Kolisek; Stefano Iotti
• Keywords: 0303 health sciences; Antibiotics, Antineoplastic; Cell Cycle; Apoptosis; Staurosporine; Mitochondria; Mitochondrial Proteins; Chemistry (miscellaneous); Biophysics; Biomaterials; Biochemistry; 2506; 03 medical and health sciences; HEK293 Cells; Doxorubicin; Humans; Magnesium; Enzyme Inhibitors; Cation Transport Proteins; Cell Proliferation

Mitochondrial Mg channel MRS2 overexpression influences Mg concentration and sensitivity to apoptosis.