Self-assembly of folic acid dextran conjugates for cancer chemotherapy

• DOI: 10.1039/c8nr04657c
• Publication Date: 2018-08-24T15:04:20Z
• Authors: Yuxiang Tang; Yihui Li; Rong Xu; Si Li; Hang Hu; Chen Xiao; Honglian Wu; Lin Zhu; Jiaxiong Ming; Zhiqin Chu; Huibi Xu; Xiangliang Yang; Zifu Li
• Keywords: Drug Carriers; Dextrans; Neoplasms, Experimental; 02 engineering and technology; 3. Good health; Drug Liberation; Mice; Folic Acid; A549 Cells; Doxorubicin; Cell Line, Tumor; Animals; Humans; Nanoparticles; 0210 nano-technology

Three-fold functionality of folic acid (FA) has been demonstrated in DOX@DEX-FA nanoparticles for cancer-targeted nanotherapeutics.