Direct N-heterocyclization of hydrazines to access styrylated pyrazoles: synthesis of 1,3,5-trisubstituted pyrazoles and dihydropyrazoles

• DOI: 10.1039/c8ra04550j
• Publication Date: 2018-07-24T10:14:14Z
• Authors: Vunnam Venkateswarlu; Jaspreet Kour; K. A. Aravinda Kumar; Praveen Kumar Verma; G. Lakshma Reddy; Yaseen Hussain; Aliya Tabassum; Shilpi Balgotra; Sorav Gupta; Abhinandan D. Hud...; Ram A. Vishwakarma; Sanghapal D. Sawant
• Keywords: Chemistry; 01 natural sciences; 0104 chemical sciences; 3. Good health

The synthesis of tri-substituted pyrazoles was achieved <italic>via</italic> direct N-heterocyclization hydrazines with metal-acetylacetonate and -dibenzylideneacetonate without using any base or additives under microwave irradiation in a single step.