Crosslinking catalytic hairpin assembly for high-contrast imaging of multiple mRNAs in living cells

Cell Survival Optical Imaging Biosensing Techniques DNA 01 natural sciences Catalysis Nanostructures 0104 chemical sciences Cross-Linking Reagents Cell Line, Tumor Humans RNA, Messenger
DOI: 10.1039/c9cc01033e Publication Date: 2019-03-07T03:04:42Z
ABSTRACT
A novel DNA nanotetrad mediated crosslinking catalytic hairpin assembly (CCHA) is reported to generate clumps of cross-linked mesh products for high-contrast and simultaneous imaging multiple mRNAs in living cells.
SUPPLEMENTAL MATERIAL
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