Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice

• DOI: 10.1039/c9fo02803j
• Publication Date: 2020-04-02T05:52:58Z
• Authors: Yina Huang; Liang Qiu; Xuan Mi; Zhihong Zhang; Di Xu; Xueying Tao; Keyu Xing; Qinglong Wu; Hua Wei
• Keywords: 0303 health sciences; Tea; Plant Extracts; Dextran Sulfate; NF-kappa B; Down-Regulation; Colitis; 3. Good health; Mice, Inbred C57BL; Disease Models, Animal; Mice; 03 medical and health sciences; Animals; Female; Inflammation Mediators; Signal Transduction

There was lots of information on anti-obesity and reduced risk of cardiovascular disease, to our best knowledge, little was known about the prevention of colitis by RPT. We firstly assessed effects of RPT on phenotypic improvements of DSS-induced colitis in mice.