Visible-light-mediated metal-free decarboxylative acylations of isocyanides with α-oxocarboxylic acids and water leading to α-ketoamides

• DOI: 10.1039/c9gc03253c
• Publication Date: 2019-10-14T14:50:03Z
• Authors: Yufen Lv; Pengli Bao; Huilan Yue; Jiang-Sheng Li; Wei Wei
• Keywords: 01 natural sciences; 0104 chemical sciences

A novel visible-light-induced and Rose Bengal catalyzed strategy has been developed for the synthesis of α-ketoamides via decarboxylative acylations of isocyanides with α-oxocarboxylic acids and water under mild conditions.