The interplay between size and valence state on the antibacterial activity of sub-10 nm silver nanoparticles

Silver nanoparticle
DOI: 10.1039/c9na00017h Publication Date: 2019-04-29T23:55:37Z
ABSTRACT
Silver nanoparticles (AgNPs) have attracted enormous interest because of their excellent antibacterial properties, low cytotoxicity and limited evidence for resistance. As a general trend, smaller are considered to stronger activity. In this work we investigate whether trend is valid the sub-10 nm region by designing synthesising three types AgNPs (∼1.87, ∼2.93 ∼6.53 nm) reveal influence size, valence state structure on potency AgNPs. We found that NPs with size having high concentration silver in first presented highest bacterial killing as well mammalian cells. The new insights study open future avenues engineering highly potent nanoantibiotics can be incorporated into advanced medical devices therapies capable protecting patients from infections.
SUPPLEMENTAL MATERIAL
Coming soon ....
REFERENCES (29)
CITATIONS (31)