Microwave-assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines: a rapid and efficient protocol for thioamides

• DOI: 10.1039/c9ra05939c
• Publication Date: 2019-09-10T14:03:34Z
• Authors: Jinyang Chen; Lan Mei; Jialing Liu; Chuntao Zhong; Binfang Yuan; Qiang Li
• Keywords: Chemistry; 01 natural sciences; 0104 chemical sciences

An efficient protocol for synthesis of thioamides was developed via the microwave-assisted iodine-catalyzed oxidative coupling dibenzyl(difurfuryl)disulfides with amines. This process is scalable and tolerates a wide spectrum amines to deliver corresponding products in moderate excellent yields 10 minutes, providing cheap rapid approach thioamides.