Brønsted acid and Pd–PHOX dual-catalysed enantioselective addition of activated C-pronucleophiles to internal dienes

• DOI: 10.1039/c9sc00633h
• Publication Date: 2019-04-17T05:04:11Z
• Authors: Sangjune Park; Nathan J. Adamson; Steven J. Malcolmson
• Keywords: Brønsted–Lowry acid–base theory; Dual role

We describe the development of Pd–PHOX-catalysed enantioselective couplings internal dienes with malononitrile and other activated C-pronucleophiles.