Metal complexes as a promising source for new antibiotics

• DOI: 10.1039/c9sc06460e
• Publication Date: 2020-02-12T12:28:36Z
• Authors: Angelo Frei; Johannes Zuegg; Alysha G. Elliott; Murray Baker; Stefan Braese; Christopher Brown; Feng Chen; Christopher G. Do...; Gilles Dujardin; Nicole Jung; A. Paden King; Ahmed M. Mansour; Massimiliano Massi; John Moat; Heba A. Mohamed; Anna K. Renfrew; Peter J. Rutledge; Peter J. Sadler; Matthew H. Todd; Charlotte E. Willans; Justin J. Wilson; Matthew A. Cooper; Mark A. T. Blasko...
• Keywords: Chemistry; info:eu-repo/classification/ddc/540; ddc:540; Chemistry & allied sciences; 616; General Chemistry; 1600 Chemistry; 540; 7. Clean energy; 3. Good health

There is a dire need for new compounds to combat antibiotic resistance: metal complexes might provide the solution. 906 metal complexes were evaluated against dangerous ESKAPE pathogens and found to have a higher hit-rate than organic molecules.